Cissna has served in the foreign service in Haiti and Sweden, and also worked in the Office of the Chief Counsel at USCIS, the White House said in an announcement.
Cissna's nomination comes as Trump continues to fill up high-level positions at federal agencies. The administration had initially been slow to fill many open jobs because of the difficulty Republicans had confirming members of Trump's Cabinet.
Trump has focused heavily on immigration enforcement in the first 11 weeks of his presidency. He has directed DHS Secretary Kelly to step up security at the border and to prioritize the deportation undocumented immigrants who have committed crimes.